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TiGenix is set for a decisive 2017 with possible EMA approval in H2 of the allogeneic stem cell therapy Cx601 to treat complex perianal fistulas in Crohn’s disease. This will trigger a €15m milestone from Takeda, the European partner; Takeda views Cx601 as a breakthrough therapy. A Phase I/II trial using stem cells to control severe sepsis, a major unmet need, has just started. Another interesting project is on acute cardiac stem cell therapy; Phase I/II data are expected in H117. The US IPO raised €31m net in 2016.
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