Worldwide Healthcare Trust is a specialist investment trust that invests in the global healthcare sector, with the objective of achieving a high level of capital growth. Gearing and derivative transactions are used to enhance capital returns and mitigate risk. Performance is measured against the MSCI World Health Care Index (sterling adjusted).
EDISON VIEW
Worldwide Healthcare Trust (WWH) delivered meaningful outperformance in FY26, with NAV and share price total returns of 10.0% and 13.1%, respectively, well ahead of the benchmark’s 1.8% return. This marked a return to form after a difficult FY25, despite healthcare stocks remaining under pressure for much of the year due to US drug pricing and tariff uncertainty. Co-managers Sven Borho and Trevor Polischuk, at global healthcare specialist OrbiMed, attribute the recovery to the trust’s continued focus on innovation and growth, particularly through biotechnology and the proprietary Biotech M&A Basket, which returned 55.9% in sterling terms and contributed 5.6pp to FY26 total return. Since launch in April 1995 to the end of FY26, WWH has generated average annual NAV total returns of 13.3%, compared with 11.0% for the benchmark. The managers believe the sector backdrop has improved following greater US policy clarity, while attractive biotech valuations, high levels of innovation and large pharma’s patent cliff should continue to support M&A activity.
Worldwide Healthcare Trust (WWH) is a conventional investment trust giving investors
a specialist, actively managed route into the global healthcare sector, and its managers aim to make money for shareholders by generating a high level of
capital growth from a diversified portfolio of global healthcare stocks. Gearing and
derivative transactions are used to enhance capital returns and mitigate risk. Generally,
WWH pays the minimum dividends required to satisfy investment trust rules, as the board prefers capital to be reinvested into the portfolio. The trust is managed
by OrbiMed, a global healthcare specialist investor with c
The investment case for Worldwide Healthcare Trust starts with OrbiMed, a global healthcare specialist whose public and private market resources give the managers access to a broad opportunity set and differentiated research. The trust’s long-term strategy favours innovation and growth, particularly through biotechnology, selective emerging markets exposure and the proprietary Biotech M&A Basket. That bias carries risk: in our June 2026 note, over the last decade, a downside capture rate of 111% implies WWH is likely to underperform by a little over 10% when healthcare stocks fall, while an upside capture rate of 99% implies broadly in-line performance when they rise. This reflects the focus on emerging biotech stocks, which have a higher beta than pharma stocks, to which WWH has below-index exposure. WWH is also exposed to political and regulatory risk.
Worldwide Healthcare Trust’s proposed annual dividend for FY26 is unchanged at 2.4p per share, paid as semi-annual distributions in January and July. The FY25 dividend was also 2.4p, down from 2.8p per share in FY24. The managers have no particular yield requirement, as the board believes the trust’s capital should be deployed in the portfolio rather than paid out as dividends. WWH generally pays the minimum dividends required to satisfy investment trust rules. Revenue per share fell to 2.2p in FY26 from 2.4p in FY25, largely due to relatively low exposure to higher-yielding stocks and a smaller portfolio following share buybacks. Revenue reserves at the end of FY26 were equivalent to c 1.9x the proposed annual distribution.
In our 24 June 2026 note, Worldwide Healthcare Trust’s then co-managers, Sven Borho and Trevor Polischuk, were positive on the outlook for global healthcare. Healthcare stocks underperformed broader markets in the first half of FY26 (April to September 2025) on US drug pricing and pharmaceutical tariff concerns. That changed materially from 30 September 2025, when the Trump administration and Pfizer announced the first of 17 agreements with biopharmaceutical companies. The managers believed this policy clarity had strengthened the case for healthcare’s relative performance to improve, though not all political risk had disappeared. In WWH’s 2026 playbook, the managers saw healthcare at a more attractive entry point than for some time. At end-May 2026, healthcare valuations looked more reasonable, with the MSCI World Health Care Index on 17.1x forward P/E, a c 13% discount to the MSCI World Index’s 19.6x. Since 3 August 2026, Trevor Polischuk has been lead portfolio manager and Geoff Hsu co-portfolio manager, following Sven Borho’s departure.
Worldwide Healthcare Trust performed well ahead of its benchmark, the MSCI World Health Care Index, in FY26 (ending 31 March). Its net asset value (NAV) and share price total returns were 10.0% and 13.1%, respectively, against the benchmark’s 1.8% total return, a significant improvement after a difficult FY25. M&A provided evidence of strategic demand for innovation, with the proprietary Biotech M&A Basket returning 55.9% in sterling terms in FY26, equivalent to 5.6pp of the trust’s total return. The long-term record remains strong: from inception in April 1995 to 31 March 2026, annualised returns were 13.3% for the NAV and 12.8% for the share price, versus 11.0% for the benchmark (Datastream World Pharma/Biotech to 30 September 2010, MSCI thereafter). In our June 2026 note, the medium-term picture is more mixed, with the five-year NAV total return still behind the benchmark, reflecting the prolonged drawdown in emerging biotech and the trust’s below-index exposure to large-cap pharma.
Worldwide Healthcare Trust’s board implemented a discount-control mechanism in 2004, aiming to ensure a maximum 6% share price discount to ex-income net asset value (NAV) in normal market conditions. It has authority, renewed annually, to repurchase up to 14.99% and allot up to 10% of issued share capital. In FY26, the trust bought back 121.1m shares, equivalent to 24.5% of the opening share base, at a cost of £396.3m and an average discount of 7.0%. Between early 2017 and the end of 2021, the shares regularly traded close to NAV and the trust issued shares when it traded at a premium. At 24 June 2026, the discount, at its widest in three years during FY25, had been narrowing since the fourth quarter of 2024, helped by an improved sector backdrop, WWH’s return to outperformance and the board’s ongoing buyback activity.
Worldwide Healthcare Trust (WWH) is managed by Sven Borho and Trevor Polischuk at global healthcare investment specialist OrbiMed. The trust aims to generate a high level of capital growth from a diversified portfolio of global healthcare stocks. It recently celebrated its 30-year anniversary, during which time, it generated a NAV total return of more than 4,200%, and a share price total return of more than 3,500%. Performance is measured against the MSCI World Health Care Index (sterling adjusted), which achieved a total return of more than 2,300% in the 30-year period.
1. Trust managers can draw on the extensive resources at OrbiMed
OrbiMed is a leading global healthcare investment company with a proven track record across public and private equity and debt markets. It has around $20bn of assets under management and 12 offices worldwide, including in New York, San Francisco, London, Herzliya (in Israel), Hong Kong, Shanghai and Mumbai. The company’s team of around 150 professionals invests in every subsector of the healthcare sector, across all geographies and at all stages of a company’s lifecycle.
2. The managers select stocks on a bottom-up basis
OrbiMed has employed a public equity portfolio review process since 2009, whereby Borho, Polischuk and colleagues in the public equities team meet regularly to discuss WWH’s portfolio structure and individual holdings. Topics include clinical and regulatory events and new drug launches. Stocks are selected from a universe of around 1,000 companies and the portfolio is diversified by geography, subsector and market capitalisation. The managers seek companies with underappreciated product pipelines and strong management teams, which are trading on reasonable valuations. They also have good access to unquoted companies, given OrbiMed’s large private equity team. There is a disciplined portfolio construction approach and a rigorous risk-management process.
3. WWH’s portfolio is biased towards growth stocks
Although the trust experienced a difficult period of performance in recent years as growth stocks struggled in a rising interest rate environment, WWH has a long-term record of significant outperformance versus its benchmark, and recent performance has been more encouraging.
The main features of the trust’s portfolio are its longstanding overweight exposure to biotech and an underweight allocation to pharma stocks. Within biotech, the managers favour emerging (smaller-cap) companies rather than larger businesses, as, although these companies are inherently riskier, their risk/reward profiles are deemed to be superior. Over the long term, this strategy has been significantly beneficial for the trust’s performance.
Innovation within the biopharma industry is strong, driven by novel therapeutic technologies and supported by the rise of AI, which the managers believe will touch almost every aspect of the sector. Two-thirds of the industry pipeline and more than 50% of new product approvals in the last decade have been sourced from biotech companies. Also, the regulatory environment remains supportive, with a record number of novel drug approvals in recent years.
WWH has benefited from robust healthcare M&A activity as several portfolio companies have been acquired at meaningful premiums, both direct holdings and those in a proprietary M&A basket. Activity should continue as pharma companies look to replenish their pipelines ahead of a major upcoming patent cliff.
4. The healthcare sector has historically provided relatively robust annual total returns
There is a wealth of opportunities in the global healthcare sector across a range of subsectors: pharmaceuticals (including speciality and generic businesses), biotechnology, medtech/devices, healthcare services and life science tools. The US is the most developed healthcare market and makes up more than 70% of the MSCI World Health Care Index. US healthcare stocks have delivered volatile and uncharacteristically poor relative performances across the past few years in a narrow market dominated by large-cap technology stocks, which may offer a compelling entry point to the sector.
Published 30 March 2026
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