Oxford BioMedica’s (OXB) LentiVector technology underpins the company’s strategy. OXB generates significant revenue from partners that utilise its technology, notably Novartis, Bioverativ, Orchard Therapeutics and Immune Design. OXB is in partnering discussions about internally developed assets.
Oxford BioMedica (OXB) is a global leader in lentiviral development and manufacturing. Maiden interim profits reported this year are evidence of strong operational momentum and ongoing validation of its business model. On the back of a £19.3m net raise in March, OXB is expanding its manufacturing capabilities to match increasing demand and continued growth of its platform (partnership) revenues. In the near term, revenue will continue to be driven by the Novartis partnership as Kymriah’s commercial roll out continues (royalties and manufacturing fees). OXB has several established development and manufacturing partnerships with Bioverativ, Sanofi & Orchard Therapeutics and continues to look to spin-out/out-license its internally developed, preclinical assets. Recently, partner Axovant announced that the development of AXO-Lenti-PD (in-licensed from OXB) was proceeding according to plan, with the first data from the ongoing SUNRISE-PD Phase II trial expected in Q119. As of 30 June, OXB had gross cash of £44.0m.
Cell- and gene-therapy is the focus of much industry attention as it can dramatically alter the outcomes of many diseases. The proprietary lentivector platform has demonstrated promise in many indications.