IRLAB Therapeutics has announced that the results from its Phase IIb clinical trial, evaluating mesdopetam as a potential treatment to address levodopa induced dyskinesias, have been published in the journal Movement Disorders Clinical Practice. The data showed both clinically meaningful and dose-dependent anti-dyskinetic effects of the candidate and, while the primary endpoint was not met (good ON-time), it was encouraging that evaluations for ON-phase dyskinesia, including the Unified Dyskinesia Rating Scale, demonstrated clinically relevant and statistically significant improvements.
Mesdopetam is IRLAB’s lead clinical candidate and, subject to securing a suitable partner, management aims to launch a Phase III programme within 2025.
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