Vivesto is a Swedish speciality pharma company focusing on its proprietary XR-17 technology platform to develop novel formulations of well-established cytostatic oncology treatments for human and animal health. Key assets include Apealea (partnered with Elevar), docetaxel micellar and Cantrixil.
Vivesto is focused on developing improved formulations of well-established cancer drugs through the application of its proprietary XR-17 platform. This solubility enhancing technology has received validation though a global partnership deal for lead asset Apealea (Cremophor-free paclitaxel) with Elevar Therapeutics across a variety of cancers. Apealea is approved in Europe for second-line ovarian cancer and will be launched by Inceptua in H122. Additional studies are expected to be required before an NDA filing in the United States. Vivesto is working on additional nanoparticle formulations, including docetaxel micellar (Phase Ib prostate cancer) and the development of innovative drugs (preclinical stage). In-licensed asset Cantrixil is expected to start Phase II development in ovarian cancer. In March, Vivesto completed a rights issue raising gross proceeds of c SEK151m, our forecasts are under review.
Despite a slew of novel cancer drugs transforming care for many oncology indications, established chemotherapy regimens remain a cornerstone of treatment. Vivesto’s XR-17 technology is applicable to any solubility limited drug, which includes 10–15 different cytostatic agents, and can potentially provide an improved formulation and profile.