Immix Biopharma’s lead asset, IMX-110, is being investigated in a Phase Ib/IIa study for the treatment of soft tissue sarcoma and a Phase Ib trial in advanced solid tumors in combination with tislelizumab. Its preclinical pipeline is based on tissue-specific therapeutics (TSTx) technology.
CAR-T cell therapies have the potential to provide effective treatments for challenging diseases. However, current available options are not considered outpatient treatments due to the risk of serious side effects. If NXC-201 continues to demonstrate a desirable efficacy and safety profile, it could become the first outpatient CAR-T cell therapy.
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Dr Ilya Rachman
CEO
Gabriel Morris
CFO
Forecast net debt (US$m)
15.1
Forecast gearing ratio (%)
N/A
% | 1M | 3M | 12M |
---|---|---|---|
Actual | (21.4) | (38.7) | (20.3) |
Relative | (19.2) | (40.0) | (35.2) |
52 week high/low | US$7.3/US$1.6 |
Immix Biopharma is focused on the development of novel CAR-T cell therapies and TSTx. The company’s lead CAR-T cell therapy asset (NXC-201) is being assessed in the Phase Ib/IIa NEXICART-1 trial for multiple myeloma and AL amyloidosis (Orphan Drug designation granted in both indications). Rolling data readouts to date have demonstrated high response rates and a desirable safety profile. The company’s lead TSTx asset (IMX-110) is being investigated for the treatment of soft tissue sarcoma in Phase Ib/IIa studies; interim results have demonstrated positive safety and efficacy profiles. IMX-110 is also being assessed for the treatment of solid tumours in the Phase Ib/IIa IMMINENT-01 combination trial with tislelizumab; positive interim results have been reported in patients with colorectal cancer. We expect rolling data readouts for both NXC-201 and IMX-110 throughout 2024.
Y/E Dec | Revenue (US$m) | EBITDA (US$m) | PBT (US$m) | EPS (c) | P/E (x) | P/CF (x) |
---|---|---|---|---|---|---|
2022A | 0.0 | (8.2) | (7.6) | (54.77) | N/A | N/A |
2023A | 0.0 | (16.1) | (13.0) | (75.14) | N/A | N/A |
2024E | 0.0 | (22.0) | (21.4) | (92.72) | N/A | N/A |
2025E | 0.0 | (26.2) | (26.5) | (100.75) | N/A | N/A |