VolitionRx is a Belgium-based diagnostics company focused on developing blood-based cancer diagnostics based on its proprietary Nu.Q™ technology. Its lead program is in colorectal cancer, which entered the European market in 2017.
VolitionRx’s proprietary Nu.Q™ technology detects the level and structure of nucleosomes in the blood using one drop of blood serum. It is currently focused on colorectal cancer (CRC), a very large opportunity with around 225 million people eligible for screening (US/EU). VolitionRx will be participating in a 13,500 undiagnosed person trial in the US to gain FDA approval for front-line CRC screening. For Europe, the company plans to market a triage screening test followed by a front-line screening test. Readouts from 4,300 and 12,000+ sample studies are expected in H218 and Q119 respectively to support a CE Mark. Volition recently announced positive data from a pancreatic cancer study with Nu.Q™. Volition also recently secured new funding: $9m private placement, $8.4m (gross) through a registered public offering of common shares and $700k from the Walloon Regional Government. Volition’s new partner Active Motif will begin to sell Nu.Q™ assay research kits which Volition hope will help to validate the assays and explore new indications.
The blood-based cancer screening market is in its nascent stages with great potential and serves an unmet medical need. Currently there are few, if any, non-invasive screening methods for the vast majority of cancers.